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RSD Alert
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Drugs |
Drugs on RSD Alert
(notes and comments from correspondents) |
Botulinum |
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Description |
NEWS ITEM - drug under development |
Side effects(Don't be unduly alarmed. All drugs cause side effects for some patients) |
{side effects} |
Warnings(These are standard cautions but may not apply in your case) |
{warnings} |
Comments |
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| September
2001 Report - Daily Telegraph, Times, Independent - "Toxin
used as a painkiller" The most poisonous substance known to science is being developed into a drug for treating chronic pain. Botulinum toxin has inspired new treatments for whiplash injury, migraine and chronic pain. Early results of laboratory trials show that one dose of the prototype can provide pain relief for weeks and even months. Scientists at the Government's Centre for Applied Microbiology Research at Porton Down in Wiltshire believe they can successfully treat chronic pain with no side effects - one of the most difficult areas in medicine. The Porton Down team is modifying the toxin so that it can target the nerve fibres in chronic pain without causing muscle weakness. The centre's director of products, Peter Hambleton, said: "Botulinum
toxins are the most potent toxins known to man. They act by preventing
the signals passing from nerves to the muscles, so inducing flaccid
paralysis which is often fatal." Botulinum toxin targets
the nerves that control muscles and it is now used for a range
of treatments, from wrinkle removal to writers' cramp and cerebral
palsy. The centre's programme director of toxins, Dr Keith Foster,
told the Science Festival: "We have experimental results
which indicate there is in fact a potential to target the toxin
to nerves responsible for pain and block their function for many
weeks. This opens up the possibility to develop novel pharmaceuticals
for the treatment of chronic pain." Provided by Derek
- West Wales |
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