Drugs

Drugs on RSD Alert

(notes and comments from correspondents)

Desryl

Description
An antidepressant, which seems to work by selectively inhibiting uptake of the brain's own neurotransmitter serotonin". It works slowly taking from 2 to 6 weeks to affect the concentration of serotonin enough to show improvements. It is classed as a triazolopyridine and is unrelated chemically to other antidepressants. Also known as Trazodone Hydrochloride, Desyrel or Desirel.
Side effects

(Don't be unduly alarmed. All drugs cause side effects for some patients)

Nausea dry mouth, heart irregularities, dizziness, nervousness, constipation, postural hypotension and sexual difficulties (e.g. occasional priapism or continuous erection).
Warnings

(These are standard cautions but may not be applicable to your case)

Use with caution for patients who have heart problems, especially those who have suffered a recent heart attack. Similar warnings cover patients with epilepsy, thyroid disorders, diabetes, impaired liver function, urinary retention or glaucoma. Also those who have had manic episodes or are mentally unstable. Not recommended for pregnant women. Withdrawal of this dug should be gradual

Comments

The one drug I am glad to have and have noticed a marked difference in is the desryl. It enables me to sleep through the night. I've taken other meds to help me sleep but the desryl is great I have to take 250mg every night. Downside I wake up kind of hung over but it doesn't last long. And is not a enough of a side effect for me to not take it. I know the vicodin and motrin help. I've tried not taking them. And notice a marked increase in the pain so they do help. Karen - Tampa, Florida, USA

After trying many antidepressents that caused sexual side effects I was finally placed on this drug. Following a bad car accident my dose was upped to 200mg a night. At first all seemed well and it seemed like a miracle drug. After about two years I had an unexplained fainting spell and hurt myself fairly badly when I fell. Tests were run and no explanation was found. Over the next two years I continued to have intermittent fainting spells. They always happen an hour or two after taking Desyrl. But since it may happen three times in one week and then not happen again for three months, my doctor did not believe they were connected to the medication. Many more tests were run; cat scans, heart tests, blood work, etc. I ran up huge medical bills but no explanation was found for the fainting spells. It was not recommended I come off the drug, but I felt it was somehow related since the spells always occur after taking Desryl. I began weaning myself off of it (at the cost of being unable to sleep) going from 200mg to 150mg to 100mg. The spells decreased in frequency but still occurred. After a particularly bad fainting episode last night, I finally started researching the drug on the web and found that postural hypotension is a side effect of this drug. I will now reduce it 50mg and get off this drug. It concerns me that none of the doctors I have seen realized (or listened to me) that this drug is what is causing the problems. Beth, Bossier City, Louisiana, USA.

www.rsdalert.co.uk
for correspondence click CONTACT