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RSD Alert
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Drugs |
Drugs on RSD Alert
(notes and comments from correspondents) |
Pregabalin |
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Description |
Also marketed under the brand name Lyrica, pregabalin is a development from the established anti-convulsant drug, Gabapentin. |
Side effects(Don't be unduly alarmed. All drugs cause side effects for some patients) |
Constipation, dizziness, drowsiness, dry mouth, fatigue, flatulence and nausea. Confusion, irritability, blurred and double vision have been reported. Possible increase to appetite with resultant weight gains. Some [atients report loss of libido. Side effects with Pregabalin are said usually to be mild to moderate and may relate to the size of the dose. |
Warnings(These are standard cautions but may not apply in your case) |
This drug may affect your ability to drive. |
Comments |
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Remember - RSD/CRPS is rooted in the nervous system. The discovery that epilepsy drugs may have beneficial effects for RSD patients does not imply that they have epilepsy. I have been taking Pregablen for over 2 years. In my case, chronic
pain from a neck injury has resulted in depression. I have never
felt the "out of body" feeling. I take three anti-depressants
and one schedule one medication. The medication has not eliminated
the pain. It may be helping, I am not sure. I have asked my health
care provider to wean me off of it. The provider did not want
me to stop taking the medication. Properly done Western style acupuncture is far superior to both
gaba (gabapentin/neurotin) & pregaba (pregabalin/Lyrica) for
people who have spinal nerve injuries and RSD affecting legs.
So is properly designed stretching & exercise routines. Both
gaba & pregaba cause issues with stability & gait and
reduce one's awareness of oneself & one's surroundings. This
only leads to further pain and vicious cramps. Personal experience,
and that of one other patient I know, pregaba actually increases
neuropathic pain! It seems to be reducing blood flow to areas
affected by damaged nerves. "Freezing" sensation in
legs is a common intermittent problem for me, as is shooting,
burning, gripping pain & cramp. Pregaba increased all these
nasty sensations at above 75mg (3x25mg) a day. Pfizer's new claim
is that pregaba is what they thought gabapentin was(!) Interesting!
My advice - if you have nerve damage or RSD affecting lower torso
& legs then I have been taking Pregabelin (Lyrica) for a number of weeks
now, along with Tramadol. I am very aware that when I take a full
dose of both drugs together, 100Mg / 150Mg tramadol and 150Mg
of Pregabelin. I feel a very strange almost "spaced out"
feeling. I certainly feel very unsteady on my feet and find it
difficult to walk a few yards without having to hold on to something
to steady myself. Like Andy frmm Taunton I had been given Tramadol on top of the highest dose of Pregabalin and had the same symptoms. I have now come off of Tramadol and am seeking a new pain killer to take over from it. I was so bad at the start of taking both drugs I could not move from a chair or open my eyes without a feeling my brain was swimming, I have had chronic in my elbows for 6 years and have forgotten what a pain free life is, if anyone has any ideas about an other pain killer please let me know. MSB - UK I have been taking Lyrica for 3 months now and find it amazingly effective. I have had RSDS/CRPS for two and half years and had constant pain in both my hands. Work was out, as were many daily routines and it was only when my Consutant prescibed the 'new' drug Lyrica, that I had the first painfree day for over 2 years. I expected the effects to diminish over the weeks but to my amazement, it is still as effective as when I started. I do have side effects (dizziness, unsteady and feeling slightly 'drunk', which led me to avoid all alcholic drink ) but these are minor to me, compared to the pain relief. Helen - Skerries, Co Dublin, Ireland I have been taking this drug a few weeks now. It certainly controls the pain and allows freer movement of my hand and fingers. I too have noticed a slight tendency to feel 'spaced out' which is quite nice really, so no complaints there, BUT, yesterday I fell over in the kitchen. My husband came rushing to help me and asked what had happened, and I didn't know. One minute walking towards the fridge, next minute on the deck with a big bruise to show for it. I have never fallen over in my life before, so am wondering about the pregabalin. Maria - Chelmsford, Essex, England I have been taking pregablin (75mg bds) for one week now. This is to replace the Gabapentin that Iam on to see if it will be more successful. I am to increase my dose by double (to 150mg bds). At the moment I feel on edge and really irritable. My wife says now I know what it is like to have PMT! I am concerned that this is a side effect of the Pregablin. Anyone experienced this? Gary - Hockley, Essex, UK I have been on 150mg of Pregabalin for 18 months and found it
an unusual experience. Initially it was very good with a release
from neuropathic pains that I had suffered for almost 30 years.
I also have been taking 50 - 150 mg Tramadol
which has also been excellent. However over the past 4 months
I have developed an issue with my sight which is currently being
out down to the Pregabalin. Reduced dosage over 4 week period
and finally stopped last weekend. OMG I forgot how painful my
spine and neck were before! |
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