Drugs

Drugs on RSD Alert

(notes and comments from correspondents)

Temgesic

Description
A narcotic analgesic, which is on the controlled Drugs list but is thought to be less addictive than e.g. Morphine. It is long lasting and the effects of one dose may last up to 12 hours. Taken orally as tablets placed under the tongue. Also marketed as Buprenorphine.
Side effects

(Don't be unduly alarmed. All drugs cause side effects for some patients)

Drowsiness, nausea, vomiting, sweating dizziness, mood changes, hypotension (low blood pressure). May precipitate withdrawal symptoms if used together with other narcotic analgesics.
Warnings

(These are standard cautions but may not apply in your case)

Should not be used for patients who have suffered head injury. Caution is needed with patients who have asthma or low blood pressure or who have impaired liver or kidney function. Care advised if the patient is in the final stages of pregnancy or is elderly.

Comments

I have very positive things to say about Temgesic (buprenorphine) In 0.2mg sublingual tabs for me it addresses the deep bone aches by at least 70%. Temgesic (buprenorphine) is largely an antagonist at low levels. This means that the brain/body does not develop a tolerance. Thus, once at a desired level you can maintain that level forever. It has a long lasting effect of at least 5 hours, no side effects just a little drowsiness. No "highs". Pam - Brisbane, Australia

I take Buprenorphine (Temgesic) and it keeps my pain within bearable limits. Martin - Liverpool, England

I have suffered on and off with the most terrible headaches for probably the last 10 years and have tried a whole range of drugs. Some of the drugs work sometimes and sometimes they don't. Recently my Doctor asked me to try Temgesic next time I had an onset of headaches.
After using Temgesic sublingual tabs, I was very impressed with the results. I got relief from the pain quite quickly and had no side affects. The following day I was completely free from any indication or aftermath of the headaches which normally I am not.
I really believe at last I have found something that works and provides relief with out any major side affects. Greg - Brisbane, Australia

I was given Temgesic 0.2 mg in 1983 at first as a rheumatic patient when nothing else could take my pains away. Using 1-4 tablets usually evening/nights, when needed, in cold, windy and damp weather, combined with low pressure (the west coast of Norway is like that for 65-70 % of the yea), the pains just "glide off" inside 25-30 minutes after intake. When the weather is good, warm and stable, or when I go south, I can stop taking them overnight and manage without until the weather brings the pain back .

I cannot see that it has given me any "secondhand problems" as other medicines used to do to me - neither dependence, nor any need for progressivley higher doses when needed. So for me it has been the ultimate solution, after the first year of trying it. Jan - Bergen, Norway

I have been taking Temgesic for the last 4 weeks, having been on various
painkillers (including morphine) since seriously injuring my back to the point that I cannot walk due to pain. I have found that Temgesic dulls my pain up to 50%. They work about 30 to 40 mins after taking. Although I still can't walk they help make my day relatively easy. Sean - Colchester, Essex, England

I have been taking Temgesic now for about 2 months. I was changed to it after informing my doctor that Nubain (the previous pain control medication he had me on before) was not working anymore. My body had built up a tolerance to it and it was no longer controlling my pain. I was in a car accident a few years ago where I lost my left leg and my right femur was replace with a transfemoral rod. All this metal inside me causes severe arthritic type pain making it difficult for me to complete many of the regular daily tasks as well as sleep. With Temgesic I am able to go to work, and get through the day painless. I also sleep much better. I don´t find I am developing any tolerance for it, although it hasn´t been all that long yet. I take it in intramuscular injections when needed, usually once in the morning and once at night (100cc doses). I am happy to read the other comments on this drug, maybe I have finally found the right one! Daniel - Puerto Vallarta, Mexico

I have suffered with severe ME/CFS for 6 years, and have tried many medications, including morphine, to help with excruciating leg muscle pain. Like others with ME, who are intolerent to many drugs, the side-effects of medication can outweigh any benefit, yet this has not happened with bruprenorphine (Temgesic). My pain is at its worst in the evening reaching a crescendo in the night, yet 30-40 minutes after taking Temgesic even entrenched pain can be "blown out " of my muscles. It gives me a relief I have not found with any other drug or holistic intervention. If you have ME with severe pain, do ask your GP about Temgesic as in the UK it is not on the small list of medications generally prescribed for the illness, and it took me several years of trial and error with a sympathetic GP and Pain Consultant to find it. Jayne - Liverpool, England
(Although Jayne does not have RSD her pain problems are similar and her comments are most helpful - Ed)


www.rsdalert.co.uk
for correspondence click CONTACT