These notes are taken from RSD Websites and medical articles which shed light on why RSD can lead to depression and information on treatment. Grateful acknowledgement is given to all sources. The extracts have been arranged in an order that presents a theoretical explanation for RSD induced depression. The author has seen the effects first hand within his own family.

Drug Treatment for Depression

SSRIs (selective serotonin reuptake inhibitors)

SSRIs act on a chemical in the brain called serotonin. They are the most commonly prescribed class of antidepressants because the adverse effects are less severe than those of older antidepressants.

Tricyclic antidepressants

Tricyclics are an older class of antidepressants than the SSRIs. The tricyclics typically take around two weeks to provide symptom relief.

MAOIs (Monoamine oxidase inhibitors)

MAOIs are the oldest class of antidepressants. Common side effects include weight gain, dizziness, drowsiness, and loss of sex drive. MAOIs also have severe interactions with certain foods, drinks, and medications. If you choose to take an MAOI, you will have to carefully monitor what you eat and what drugs you take. Items that are restricted include many cheeses, chocolate, wine, and beer.

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© Tim Anderson 2007